Forsythoside B( —— )

Catalog No. M19137 CAS No. 81525-13-5

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Group Booking Get Quotation Bulk Inquiry Add to Cart

Product Name

Forsythoside B
Note

Research use only, not for human use.
Brief Description

Forsythoside B binds to LPS and reduces the biological activity of serum LPS, and inhibits NF-κB activation. Forsythoside B inhibits the inflammatory response and has antioxidant properties.
Description

Forsythoside B binds to LPS and reduces the biological activity of serum LPS, and inhibits NF-κB activation. Forsythoside B inhibits the inflammatory response and has antioxidant properties. Potent neuroprotective effects with a favorable therapeutic time-window, reduce of cerebral ischemia and reperfusion injury degree, attenuating blood-brain barrier (BBB) breakdown; Rescued cardiac function from I/R injury. Forsythoside B has antisepsis effect, is mediated by decreasing local and systemic levels of a wide spectrum of inflammatory mediators.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Apoptosis
Target

NF-κB
Recptor

NF-κB
Research Area

Inflammation/Immunology
Indication

——

CAS Number

81525-13-5
Formula Weight

756.71
Molecular Formula

C34H44O19
Purity

>98% (HPLC)
Solubility

DMSO : 125 mg/mL 165.19 mM
SMILES

O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO[C@@H]1OC[C@]([C@H]1O)(O)CO)OC(=O)/C=C/c1cc(c(cc1)O)O)O[C@@H]1O[C@H]([C@@H]([C@H]([C@H]1O)O)O)C)O)OCCc1cc(c(cc1)O)O
Chemical Name

——

1. Jiang WL,et al. Forsythoside B protects against experimental sepsis by modulating inflammatory factors. Phytother Res. 2012 Jul;26(7):981-7.

Calculator

molnova catalog